Xeloda

Xeloda is a cancer medicine that interferes with the growth of cancer cells and slows their spread in the body. Xeloda is used to treat colon cancer, and breast or colorectal cancer that has spread to other parts of the body. Xeloda is often used in combination with other cancer medications and/or radiation treatments.

You should not take Xeloda if you have severe kidney disease or a metabolic disorder called DPD (dihydropyrimidine dehydrogenase) deficiency.

If you take a blood thinner, you may need to have more frequent "INR" or prothrombin time tests. Taking a blood thinner can increase your risk of severe bleeding while you are using Xeloda, and for a short time after you stop taking this medicine. This risk is higher in adults older than 60.

You should not take Xeloda if you are allergic to Capecitabine or Fuorouracil, or if you have: severe kidney disease; or a metabolic disorder called DPD (dihydropyrimidine dehydrogenase) deficiency. 

To make sure Xeloda is safe for you, tell your doctor if you have any of these conditions: kidney disease; bleeding or blood clotting disorder such as hemophilia; liver disease; a history of coronary artery disease; or if you take a blood thinner. Do not use Xeloda if you are pregnant. It could harm the unborn baby.

Use birth control to prevent pregnancy while you are taking Xeloda, whether you are a man or a woman. Tell your doctor if a pregnancy occurs during treatment. It is not known whether capecitabine passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are taking Xeloda.

Xeloda is usually taken twice per day. Follow the directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. Xeloda is given in a 3-week treatment cycle, and you may only need to take the medicine during the first 2 weeks of each cycle. Your doctor will determine how long to treat you with Xeloda. Xeloda is only part of a treatment program that may also include other medications taken on different schedules. Follow your doctor's dosing instructions very carefully.

Xeloda should be taken with food or within 30 minutes after eating a meal. Take Xeloda with a full glass (8 ounces) of water.

Call your doctor if you are sick with vomiting or diarrhea, if you are unable to eat because of stomach illness, or if you are sweating more than usual. Prolonged illness can lead to dehydration or kidney failure.

You may need frequent medical tests to be sure this medicine is not causing harmful effects. Your cancer treatments may be delayed based on the results of these tests. Xeloda can have long lasting effects on your body. You may need frequent medical tests for a short time after you stop using this medicine. You must remain under the care of a doctor while you are taking Xeloda.

Store Xeloda at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions. Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

Call your doctor at once if you have: fever above 100.5 degrees; nausea, loss of appetite, eating much less than usual, vomiting (more than once in 24 hours); severe diarrhea (more than 4 times per day, or during the night); blisters or ulcers in your mouth, red or swollen gums, trouble swallowing; pain, tenderness, redness, swelling, blistering, or peeling skin on your hands or feet; dehydration symptoms - feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin; heart problems - chest pain or pressure, uneven heartbeats, shortness of breath (even with mild exertion), swelling or rapid weight gain; kidney problems - little or no urinating; painful or difficult urination; swelling in your feet or ankles; feeling tired or short of breath; liver problems - nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes); low blood cell counts - fever or other flu symptoms, cough, skin sores, pale skin, easy bruising, unusual bleeding, feeling light-headed, rapid heart rate; or severe skin reaction - fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Common Xeloda side effects may include: stomach pain or upset, constipation; tired feeling; mild skin rash; or numbness or tingling in your hands or feet.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.